New therapy for Alzheimer’s: magnetic stimulation slows disease progression
The treatment, non-invasive and personalized, was carried out in two phases: an initial intensive cycle involved daily applications for 2 weeks; subsequently, in a maintenance phase, TMS was applied once a week for 50 weeks.
The personalization of the rTMS treatment was made possible thanks to the use of advanced neurophysiological methods such as TMS in combination with electroencephalography (TMS-EEG), which made it possible to define, for each patient, the optimal point and intensity of stimulation for rTMS, by integrating the information obtained with the patient’s magnetic resonance imaging.
Before and after the 52-week rTMS cycle, clinical evaluation scales were used to assess cognitive disorders (CDR-SB, ADAS-Cog11), autonomy in daily life (ADCS-ADL), and behavioral disorders (NPI).
